Controlled intracellular trafficking alleviates an expression bottleneck in S. cerevisiae ester biosynthesis

Modular TRAPP complexes regulate intracellular protein trafficking through multiple Ypt/Rab GTPases in S. cerevisiae

Biosynthesis of Zinc Oxide Nanoparticles using Intracellular Extract of Saccharomyces cerevisiae and Evaluation of its Antibacterial and Antioxidant Activities

Introduction: Attention to the biosynthesis of nanoparticles (NPs) has been increased recently since they are cost-effective, eco-friendly, and potential alternatives to chemical and physical methods. This study aimed to synthesize zinc oxide nanoparticles (ZnO NPs) using an intracellular extract of Saccharomyces cerevisiae. Moreover, it was attempted to evaluate their antibacterial and antioxi...

Intracellular trafficking.

Studies in C. elegans have begun to reveal new components and new mechanisms associated with intracellular membrane traffic in a variety of cell types. The worm benefits from many of the advantages of yeast as a genetically tractable organism for these kinds of studies while offering the unique opportunity to probe how these pathways have been extended and modified in the context of a multicell...

Differences in growth promotion, drug response and intracellular protein trafficking of FLT3 mutants

Objective(s): Mutant forms FMS-like tyrosine kinase-3 (FLT3), are reported in 25% of childhood acute lymphoid leukemia (ALL) and 30% of acute myeloid leukemia (AML) patients. In this study, drug response, growth promoting, and protein trafficking of FLT3 wild-type was compared with two active mutants (Internal Tandem Duplication (ITD)) and D835Y. Materials and Methods:FLT3 was expressed on fact...

Intracellular Biosynthesis of Gold Nanoparticles by the Fungus Penicillium Chrysogenum

In this study, the biosynthesis of gold nanoparticles by Penicillium chrysogenum, isolated from Ahar copper mine, was investigated. The gold nanoparticles were synthesized by reducing the aqueous gold ions using the culture supernatant of the filamentous fungi. The UV–vis spectrum displayed a characteristic peak at 532 nm that is very specific for gold nanoparticles. The XRD spectrum confirmed ...